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国际呼吸杂志

创刊年:1981年

刊   期:半月刊

主   编:阎锡新

主   任:张雷

地   址:石家庄市中山东路361号

邮   编:050017

电   话:0311-86266873

E- mail:guojihuxi@vip.163.com

网   址:www.guojihuxi.com

邮发 代号:18-12

中国连续出版物号:ISSN 1673-436X

CN 13-1368/R

2012 年   第 32 卷   第 4 期   半月刊

肺癌化疗耐药相关性生物标志物与个体化治疗

倪磊,冯耘,万欢英

【文章下载】

  [摘要] 化疗是晚期肺癌的主要治疗方式,但对于非小细胞肺癌及复发的小细胞肺癌化疗有效率仍较低,肿瘤细胞的多药耐药性是化疗失败的主要原因。目前认识到肿瘤细胞的耐药是一个复杂的多因素参与过程,目前已证实一些耐药相关性生物标志物与肿瘤的化疗敏感性预测、患者预后相关。基于生物标志物的肺癌化疗方案选择将为个体化治疗带来希望。

  [Abstract]

  [关键词] 肺癌;化疗;多药耐药;生物标志物

  [Key words]

  [中图分类号]

  [DOI]

  [基金项目]

  [作者简介]

  [作者单位] 上海交通大学医学院附属瑞金医院呼吸科,200025

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