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国际呼吸杂志

创刊年:1981年

刊   期:半月刊

主   编:阎锡新

主   任:张雷

地   址:石家庄市中山东路361号

邮   编:050017

电   话:0311-86266873

E- mail:guojihuxi@vip.163.com

网   址:www.guojihuxi.com

邮发 代号:18-12

中国连续出版物号:ISSN 1673-436X

CN 13-1368/R

2008 年   第 28 卷   第 13 期   半月刊

中药四妙丸加味治疗痛风的临床观察

宁波%王新宴%王文清

【文章下载】

  [摘要] 目的 探讨痛风及高尿酸血症患者的异同及四妙丸加味治疗痛风的机制.方法 观察30例缓解期痛风患者、32例高尿酸血症患者和31名健康对照者超敏C反应蛋白(hsCRP)、胰岛素抵抗、尿酸、胆固醇、甘油三酯的区别.痛风组服用中药四妙丸加味14 d后复查hsCRP、胰岛素抵抗和尿酸.结果 痛风组hsCRP显著高于高尿酸血症组及健康对照组(P<0.01),服用中药治疗后痛风组hsCRP显著下降(P<0.01),尿酸变化无统计学意义.结论 中药四妙丸加味可能是通过减轻炎症反应达到治疗目的 .

  [Abstract] Objective To investigate difference between gout and hyperuricemia patients and mechanism of treatment of Chinese herbal medicine Jiaweisimiaowan on gout.Methods Gout group(n=30),simple hyperuricemia group(n=32)and control group(n=31)were observed.Patients of gout group took Jiaweisimiaowan for 14 days.Levels of blood high sensitive C reactive protein(hsCRP),resistance of insulin,uric acid,cholesterol and triglycerides were measured.Results hsCRP in gout group was obviously higher than that in hyperuricemia group and control group(P<0.01).There were no difference in resistance of insulin,cholesterol and triglycerides between gout and hyperuricemia group.hsCRP in gout group was obviously lower after taking Jiaweisimiaowan while uric acid did not change.Conclusions Jiaweisimiaowan has effect of anti-inflammation on gout patients.

  [关键词] 尿酸%痛风%中草药%治疗

  [Key words] Uric acid%Gout%Chinese herbal medicine%Treatment

  [中图分类号]

  [DOI]

  [基金项目]

  [作者简介]

  [作者单位] 空军总医院重症监护科,北京,100036

【参考文献】 gwyx-hxxt200813008

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